Organ Improver 
The white-skull Organ Improver is an alchemy result with four green runes. With Practical Potions researched it turns any skin, bones, skull, heart, brain or guts into the version of that organ with the most white skulls, 3 of them, at the Formulation Bench; skin, bones and skull need Anatomy mastery 5, the other three 7. White skulls are what a buried body’s grave quality is capped by (see Graveyard).
Until you have both the Formulation Bench, from Church Lighting I, and Practical Potions (100 green, 100 blue, after Alchemy, Advanced), a mix only gives 4 green tech points and progress toward the Alchemist inspiration. At the Laboratory I it is easy to make: 2 Flour, 2 Onions, or one of each.
How to obtain
Mix
Runes 4 ·Crafted at Laboratory I
| Ingredient |
|---|
 Swamp mushroom + Swamp mushroom |
 Flour + Swamp mushroom |
| Flour + Flour |
136 ingredient combinations reach these runes — see how mixing works →
Traders
| Name | Tier | Stock |
|---|---|---|
| Alchemist · town building — build it first | Tier II | 10 |
| Alchemist · town building — build it first | Tier III | 10 |
Other sources, out of reach (1)
Craft
| Workbench | Ingredients | Yields | Duration | Tech points |
|---|---|---|---|---|
| — |  Alcohol ×1  Comet's Tail ×1 | ×2 | 6 | 12 |
Used for
Ingredient for
| Workbench | Ingredients | Outputs | Mastery | Duration | Tech points |
|---|---|---|---|---|---|
| Formulation Bench |  Bones any quality ×1  Organ Improver ×1 | Bones ★★★  13 ×1 |  5 | 6 | 12 |
| Formulation Bench |  Brain any quality ×1 Organ Improver ×1 |  Brain ★★★ 3 ×1 | 7 | 8 | 13 |
| Formulation Bench |  Guts any quality ×1 Organ Improver ×1 |  Guts ★★★ 13 ×1 | 7 | 8 | 13 |
| Formulation Bench |  Heart any quality ×1 Organ Improver ×1 |  Heart ★★★ 3 ×1 | 7 | 8 | 13 |
| Formulation Bench |  Skin any quality ×1 Organ Improver ×1 | Skin ★★★ 13 ×1 | 5 | 6 | 12 |
| Formulation Bench |  Skull any quality ×1 Organ Improver ×1 | Skull ★★★ 3 ×1 | 5 | 6 | 12 |
Study
| Study requires: | Tech points | Duration |
|---|---|---|
| Science ×15 | 1050 | 6 ( Researcher −2 ) |
Each item is studied once, on the Study Table. Studying does not use the item up. With the Scientist perk, a 30% chance of a Story.